細胞毒霉素是一種可滲透進(jìn)入細胞的真菌代謝產(chǎn)物，可以抑制肌動(dòng)蛋白聚合。這會(huì )干擾諸如細胞運動(dòng)、生長(cháng)、吞噬作用、顆粒釋放和分泌等多種過(guò)程。其中，細胞松弛素D是一種可滲透進(jìn)入細胞的抑制劑，它能夠結合肌動(dòng)蛋白絲而不是單體肌動(dòng)蛋白，在低至0.2微米的濃度下抑制聚合反應。通過(guò)這種方式，它可以阻止腫瘤細胞的遷移。

產(chǎn)品性質(zhì)：

Cas No.：22144-77-0

別名：細胞松弛素D; Zygosporin A; NSC 209835

化學(xué)名： (3S,3aR,4R,6R,6aS,7E,10R,12S,13Z,15R,15aS)-3-benzyl-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-1,11-dioxo-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-1H-cycloundeca[d]isoindol-15-yl acetate

Canonical SMILES： O[C@@H]1[C@@H](/C=C/C[C@@H](C)C2=O)[C@]3([C@@H](C=C[C@]2(C)O)OC(C)=O)[C@@H]([C@@H](C)C1=C)[C@H](CC4=CC=CC=C4)NC3=O

分子式：C30H37NO6

分子量：507.63

溶解度：10mg/mL in dichloromethane,100 mg/ml in DMSO

儲存條件：Store at -20°C, protect from light

注意事項：

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Reference:

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